Publications

Grabe G.J., Giorgio R., Wieczór M., Gollan B., Sargen M., Orozco M., Hare S., Helaine S. Molecular Stripping Underpins Derepression of a Toxin-Antitoxin System. Nature Structural and Molecular Biology (2024)
Worm D.J., Grabe G.J., de Castro G.V., Rabinovich S., Warm I., Isherwood K., Helaine S., Barnard A. Stapled Phd Peptides Inhibit Doc Toxin Induced Growth Arrest in Salmonella. ACS Chemical Biology (2023)
de Castro G.V., Worm D.J., Grabe G.J., Rowan F.C., Haggerty L., de la Lastra A.L., Popescu O., Helaine S., Barnard A. Characterization of the Key Determinants of Phd Antitoxin Mediated Doc Toxin Inactivation in Salmonella. ACS Chemical Biology (2022)
Springstein B.L., Deighan P., Grabe G.J., Hochschild A. A Bacterial Cell-Based Assay To Study SARS-CoV-2 Protein-Protein Interactions. mBio (2021)
Grabe G.J., Giorgio R.T., Hall A.M.J., Morgan R.M.L., Dubois L., Sisley T.A., Rycroft J.A., Hare S.A., Helaine S. Auxiliary interfaces support the evolution of specific toxin-antitoxin pairing. Nature Chemical Biology (2021)
Matthews-Palmer T.R.S., Gonzalez-Rodriguez N., Calcraft T., Lagercrantz S., Zachs T., Yu X., Grabe G.J., Holden D.W., Nans A., Rosenthal P.B., Rouse S.L., Beeby M. Structure of the cytoplasmic domain of SctV (SsaV) from the Salmonella SPI-2 injectisome and implications for a pH sensing mechanism. Journal of structural biology (2021)
Gollan B., Grabe G., Michaux C., Helaine S. Bacterial persisters and infection: past, present, and progressing. Annual review of microbiology. (2019)
Yu X., Grabe G.J., Liu M., Mota L.J., Holden D.W. SsaV Interacts with SsaL to Control the Translocon-to-Effector Switch in the Salmonella SPI-2 Type Three Secretion System. mBio (2018)
Rycroft J.A., Gollan B., Grabe G.J., Hall A., Cheverton A.M., Larrouy-Maumus G., Hare S.A., Helaine S. Activity of acetyltransferase toxins involved in Salmonella persister formation during macrophage infection. Nature Communications (2018)
Grabe G.J., Zhang Y., Przydacz M., Rolhion N., Yang Y., Pruneda J.N., Komander D., Holden D.W., Hare S.A. The Salmonella effector SpvD is a cysteine hydrolase with a serovar-specific polymorphism influencing catalytic activity, suppression of immune responses, and bacterial virulence. Journal of Biological Chemistry (2016)
Rolhion N., Furniss R.C.D., Grabe G., Ryan A., Liu M., Matthews S.A., Holden D.W. Inhibition of Nuclear Transport of NF-ĸB p65 by the Salmonella Type III Secretion System Effector SpvD. PLoS Pathogens (2016)